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WPATH 8 is candid on this point: "Given the lifelong implications of medical treatment and the young age at which treatments may be started, adolescents, their parents, and care providers should be

informed about the nature of the evidence base. It seems reasonable that decisions to move forward

with medical and surgical treatments should be made carefully. Despite the slowly growing body

of evidence supporting the effectiveness of early medical intervention, the number of studies is still

low, and there are few outcome studies that follow youth into adulthood. Therefore, a systematic

review regarding outcomes of treatment in adolescents is not possible."

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